| Autor: |
FALCÃO, Michelle Miranda Lopes, PIRES, Alessandra Laís Pinho Valente, LIMA-ARSATI, Ynara Bosco de Oliveira, ARSATI, Franco, de OLIVEIRA, Rodrigo Tripodi CALUMBY Ana Carla Barbosa, FREITAS, Valéria Souza |
| Zdroj: |
Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jun2024, Vol. 137 Issue 6, pe276-e277, 2p |
| Abstrakt: |
To estimate the network structure of 21 symptoms of anxiety and depression in individuals diagnosed with oral lichen planus (OLP) and compare it with salivary biomarkers. A case-control study was performed, with 21 cases with OLP, and 21 controls. Beck Anxiety and Depression Inventories were administered. Levels of salivary cortisol and alfa-amylase were determined. The Fisher and Pearson's χ2 tests were used to compare the distribution of participants´ answers to the items in the instruments. Regarding network analysis, data were statistically analyzed using regularized partial correlation network models. The shaky/unsteady symptom was the most central within the network of anxiety symptoms of individuals with the disease and, in relation to depression symptoms, feelings of punishment and self-criticism. When exploring the relationship between cortisol and alpha-amylase, weak relationships were found. When comparing the network structures of cases and controls, the networks of anxiety symptoms did not differ between groups (p = 0.18). For depression, the global strength showed that the network of the control group was more connected (69.29 vs. 27.35, p < 0.000). The network approach brings a new methodological way to explore symptom configurations. Financial support for this research was provided by the FAPESB. [ABSTRACT FROM AUTHOR] |
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