THE POLYMERASE CHAIN REACTION TEST AS AN AID IN THE DIAGNOSIS OF ORAL LESIONS IN HOSPITALIZED PATIENTS.

Autor: AGATTI, Larissa Araujo, GOBBI, Marcella Ferreira, BERGAMIN, Lívia Goron, BEZINELLI, Letícia Mello, EDUARDO, Fernanda de Paula
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jun2024, Vol. 137 Issue 6, pe265-e266, 2p
Abstrakt: The polymerase chain reaction (PCR) is a molecular technique used to amplify and detect the DNA or RNA of a pathogen in a biological sample. PCR has been widely used for the diagnosis of viral, bacterial, and fungal diseases, including COVID-19, HIV, hepatitis B and C, and tuberculosis, among others. The appearance of lesions in the oral cavity during the hospitalization of patients is common. PCR is useful for diagnosis and effective and safe treatment for the patient. We analyzed 189 medical records of patients admitted to the ICU and found 18 cases (9.5%) with oral lesions suggestive of viral etiology. In 11 patients, a reverse transcription PCR viral panel of the lesion was performed. Based on its results, we found that 72.7% were positive for herpesviruses. PCR is an important technique to aid in the diagnosis and treatment of hospitalized patients. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index