EXTENSIVE NEUROFIBROMA ON THE PALATE IN NEUROFIBROMATOSIS TYPE 1: A CASE REPORT.

Autor: FLORIANO, Alana Rayne Santos, BOAL, Juliana Glaser, LIMA, Tuanny, VENDRUSCOLO, Joana Leticia, de LIMA, Heliton Gustavo, de ARAUJO, Melissa Rodrigues
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jun2024, Vol. 137 Issue 6, pe231-e231, 1p
Abstrakt: Neurofibromatosis type 1 (NF1) is a hereditary condition arising from mutations in the NF1 gene, which encodes a tumor suppressor protein. A 67-year-old female, diagnosed with neurofibromatosis since a young age, presented with multiple hyperpigmented skin macules and numerous cutaneous nodules. She expressed difficulty in eating due to a mass on her palate. Oral examination revealed a soft tissue mass, measuring approximately 2.5cm, located on the right side of the hard palate. Cone beam computed tomography did not indicate any involvement of the underlying bone. An incisional biopsy and subsequent histopathological analysis confirmed the diagnosis of neurofibroma, with no signs of malignant transformation. The lesion was completely excised under local anesthesia, employing a high-power surgical laser (diode laser 808nm, 2000W). Following the surgical procedure, histopathological examination reaffirmed the diagnosis of neurofibroma. The patient has been under follow-up for 7 months. While the recurrence rate for neurofibromas is generally low, close and ongoing monitoring remains essential. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index