| Abstrakt: |
A 21-year-old female patient with leucoderma sought the oral medicine service, complaining of blisters in the sublingual region. Intraoral examination revealed bilateral bullous lesions with a soft consistency and a color similar to the adjacent tissue. An incisional biopsy was performed since all pre-surgical tests fell within normal limits. The histopathological report indicated a mucous extravasation cyst with the presence of lymphocytic sialadenitis, prompting further clinical and laboratory investigation. Laboratory tests included assessments for rheumatoid factor, anti-SS-B, and anti-SS-A, which yielded abnormal results, suggesting Sjögren Syndrome. The patient was subsequently referred for rheumatologic and ophthalmologic evaluations, confirming an early onset of Sjögren Syndrome. Additional immunohistochemical analysis employing markers such as Bcl2, CD10, CD20, CD138, Kappa, CD3, EBV, and Ki67, led to the diagnosis of follicular lymphoma grade II. Bilateral surgical removal of the remaining sublingual tissue was carried out, and the patient continues to receive interdisciplinary follow-up care up to the present date. [ABSTRACT FROM AUTHOR] |
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