PEDIATRIC ANGIOLEIOMYOSARCOMA OF THE ORAL CAVITY: CASE REPORT.

Autor: FRANCO, Jose Victor Duarte, PEDREÑO, Juliana dos Santos, LIMA, Gustavo Ian Correa, PINHEIRO, Tiago Novaes, De Vasconcelos II, Antonio Jorge Araujo, CABRAL, Lioney Nobre, VIEIRA, Myrian Salles
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jun2024, Vol. 137 Issue 6, pe174-e174, 1p
Abstrakt: Angioleiomyosarcomas are considered an exceptionally rare neoplasm in pediatric patients, displaying an unusual oral manifestation. We present a case of angioleiomyosarcoma in a 9-year-old boy. Upon oral examination, a pedunculated nodal mass was observed, presenting erythematous discoloration, firm consistency, and occupying the floor of the mouth. The patient reported localized pain and fever in the five days leading up to the initial clinical visit, with a lesion progression spanning six months. Evaluation via CT scan revealed a diffuse radiolucency in the furcation and alveolar ridge of tooth 84. The patient underwent an excisional biopsy. Subsequent to the histopathological diagnosis, immunohistochemical analysis employing markers such as smooth muscle actin, CD31, Caldesmon, S100, P53, Ki67 confirmed it to be a high-grade angioleiomyosarcoma. The patient was subsequently referred to a specialized pediatric oncology hospital and has been under periodic follow-up for the past six months, showing no signs of relapse to date. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index