PEMPHIGUS VULGARIS: REFRACTORY SKIN LESIONS DIAGNOSED FROM ORAL LESIONS.

Autor: MORAIS, Weslaynne Nepomuceno Lemes de Paula, CINTRA, Maria Letícia, MORAES, Maria Luzia dos Santos Firmino, MONTALLI, Victor, SPERANDIO, Marcelo, JUNQUEIRA, José Luiz Cintra, MORAES, Paulo de Camargo
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jun2024, Vol. 137 Issue 6, pe168-e168, 1p
Abstrakt: A 66-years old white female presented with a 2-month history of mouth ulcers. Her gums were bleeding and causing discomfort, making oral hygiene difficult. She also reported reddish skin blisters on her back for over a year. The patient reported being seen by several specialists who were unable to reach a diagnosis, and at the time of the examination, a patch test investigation was being conducted due to the hypothesis of an allergy. On intraoral examination, positive Nikolsky sign was observed, with the epithelium detaching easily (attached video). A biopsy was taken for direct immunofluorescence, which lead to a diagnosis of Pemphigus Vulgaris. The patient is currently under medical follow-up with oral corticosteroid (Prednisone) therapy and mouth rinses with 0.05% clobetasol propionate, as well as photobiomodulation, showing significant improvement with disappearance of cutaneous lesions andimprovement of gingival lesions. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index