INFERIOR ALVEOLAR NERVE PARESTHESIA AS THE FIRST SIGN OF MULTIPLE MYELOMA - CASE REPORT.

Autor: de CARVALHO, Estephani MARTINS Barcellos, RODRIGUES, Bruno Teixeira Gonçalves, RAMOA PIRES, Fábio, MEDEIROS, Paulo José d´Albuquerque, da SILVA, Marcele CRUZ
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jun2024, Vol. 137 Issue 6, pe158-e159, 2p
Abstrakt: Multiple myeloma (MM) is a neoplastic proliferation of plasma cells with systemic repercussions and osteolytic lesions - which may cause inferior alveolar nerve (IAN) paresthesia when located in the mandible. Therefore, we report a case of a 52-year-old female who was referred for evaluation of a periapical lesion and IAN paresthesia. The extraoral physical exam showed mild swelling on the right hemiface. Intraorally, there was no alteration. A panoramic radiography revealed an ill-defined radiolucency located in the right mandibular ramus. Blood tests showed the presence of M-protein in the serum and hypocalcemia. An incisional biopsy was performed under local anesthesia, and the histological and immunohistochemical diagnosis was Plasmacytoma. The patient was referred to the hematologist to investigate other lesions, and a costal arch biopsy also diagnosed a plasma cell tumor. Thus, the MM diagnosis was established. Dentists should be aware of MM as oral manifestations could be the first signs of the disease. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index