The added value of positron emission mammography in the assessment of the axillary lymph nodes of the pathologically proven breast cancer.

Autor: Hammad, Ghada Fathy, Radwan, Amira Hamed, Shetat, Ola Magdy, Mohamed, Ghada, Ebraheem, Maher Hassan, Gomaa, Mohamed Mohamed
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Zdroj: Egyptian Journal of Radiology & Nuclear Medicine; 6/6/2024, Vol. 55 Issue 1, p1-9, 9p
Abstrakt: Background: The staging and management of patients with breast cancer are significantly influenced by the pathological state of the axillary lymph nodes (ALN). Thus, it is very desirable to have a differential diagnosis of metastatic ALN. Purpose: The aim of this research is to assess the effectiveness of non-invasive ALN staging using PEM versus traditional breast mammography and ultrasound in patients presenting with early-stage breast cancer. This study focuses on determining if PEM can reliably stage ALNs and potentially eliminate the need for more invasive methods. Methods: In a study involving 94 breast cancer patients, PEM was used to assess ALNs. The nodes were visually evaluated for positive or negative uptake, and further categorized as non-specific, indeterminate, or malignant based on their maximum uptake values. This classification was then compared with histopathological results. Results: There were a total of 94 breast cancer patients; the results from PEM demonstrated an ALN detection sensitivity of 83.3%. The specificity of PEM in this context was found to be 98.08%, and the overall accuracy rate was 91.49%. Additionally, the Positive Predictive Value (PPV) was calculated to be 97.2%, and the Negative Predictive Value (NPV) was 87.9%. Conclusions: The initial study has shown encouraging outcomes in terms of accurate lymph node assessment. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index
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