Characteristics of clinical-pharmacological recommendations in psychiatry in Germany.

Autor: Schröder, Sebastian, Westhoff, Martin Schulze, Pfister, Tabea, Bleich, Stefan, Wedegärtner, Felix, Krüger, Tillmann H. C., Heck, Johannes, Groh, Adrian
Zdroj: International Journal of Psychiatry in Medicine; May2024, Vol. 59 Issue 3, p393-405, 13p
Abstrakt: Objective: Psychiatric patients in general, and elderly psychiatric patients in particular, are at risk of adverse drug reactions due to comorbidities and inappropriate polypharmacy. Interdisciplinary and clinical-pharmacologist-led medication reviews may contribute to medication safety in the field of psychiatry. In this study, we reported the frequency and characteristics of clinical-pharmacological recommendations in psychiatry, with a particular focus on geriatric psychiatry. Method: A clinical pharmacologist, in collaboration with the attending psychiatrists and a consulting neurologist, conducted interdisciplinary medication reviews in a general psychiatric ward with a geropsychiatric focus at a university hospital over a 25- week period. All clinical and pharmacological recommendations were recorded and evaluated. Results: A total of 316 recommendations were made during 374 medication reviews. Indications/contraindications of drugs were the most frequently discussed topics (59/316; 18.7 %), followed by dose reductions (37/316; 11.7 %), and temporary or permanent discontinuation of medications (36/316; 11.4 %). The most frequent recommendations for dose reduction involved benzodiazepines (9/37; 24.3 %). An unclear or absent indication was the most common reason for recommending temporary or permanent discontinuation of the medication (6/36; 16.7 %). Conclusion: Interdisciplinary clinical pharmacologist-led medication reviews represented a valuable contribution to medication management in psychiatric patients, particularly the elderly ones. [ABSTRACT FROM AUTHOR]
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