| Autor: |
Packiaraj Don Disouza, Francis, Alagarsamy, Saranvignesh, Chen, Tse-Wei, Chen, Shen-Ming, Liou, Wen-Chin, Lou, Bih-Show, Al-onazi, Wedad A., Ajmal Ali, M., Elshikh, Mohamed S |
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| Zdroj: |
Journal of Industrial & Engineering Chemistry; Jul2024, Vol. 135, p406-415, 10p |
| Abstrakt: |
[Display omitted] • Hydrothermally synthesized BiOCl was ultrasonically combined with hollow-shaped f-CNT for the detection of pharmaceutical drug AAP. • BiOCl/f-CNT electrocatalytic activity for AAP was assessed using CV and DPV techniques. • This sensor demonstrated wide linear ranges with low detection limits. Acetaminophen (AAP) is well recognized as a pharmaceutical agent but prolonged consumption of AAP causes serious health issues for human beings. Herein we focus on BiOCl implanted with functionalized carbon nanotube (f-CNT) used to predict AAP levels in the human body samples by electrochemical detection. Bismuth Oxy Chloride (BiOCl) improves electrochemical performance with its electrochemical active sites, it suffers from sluggish kinetics with electron transfer. The composites of BiOCl and f-CNT are well-dispersed substantially, and the synergistic interface between BiOCl and f-CNT improves the electron transfer properties, alongside the catalytic activity enhanced with the large surface area of f-CNT. Notably, the BiOCl/f-CNT/Glassy carbon electrode (GCE) composite exhibits an excellent redox AAP detection in the electrochemical methods of cyclic voltammetry and different pulse voltammetry in pH-7.0 phosphate buffer solution at 0.4 V. The BiOCl/f-CNT composite achieves an outstanding lower detection limit of 0.0016 µM with a wide linear range of 0.01 to 650 µM of AAP with a higher sensitivity of 0.8754 µA µM−1 cm−2. Moreover, composite additionally depicts good selectivity and outstanding repeatability, reproducibility, and strong stability. However, human urine and blood serum gain insights into the clinical detection of AAP with an Acceptable recovery range. [ABSTRACT FROM AUTHOR] |
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