Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers.
| Autor: | Cottrell, Kevin M., Briggs, Kimberly J., Whittington, Douglas A., Jahic, Haris, Ali, Janid A., Davis, Charles B., Gong, Shanzhong, Gotur, Deepali, Gu, Lina, McCarren, Patrick, Tonini, Matthew R., Tsai, Alice, Wilker, Erik W., Yuan, Hongling, Zhang, Minjie, Zhang, Wenhai, Huang, Alan, Maxwell, John P. |
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| Zdroj: | Journal of Medicinal Chemistry; 4/25/2024, Vol. 67 Issue 8, p6064-6080, 17p |
| Databáze: | Supplemental Index |
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