| Autor: |
Frey, Rebecca K., Wehtje, Morgan E., Nol, Pauline, Clarke, Patrick R., Rhyan, Jack C., McCollum, Matthew P., Miller, Lowell A., Eckery, Douglas C. |
| Zdroj: |
Journal of Wildlife Diseases; Apr2024, Vol. 60 Issue 2, p339-345, 7p |
| Abstrakt: |
The purpose of this study was to determine if the number of pregnancies in naturally infected Brucella abortus–positive bison (Bison bison) cows would be reduced over a period of 5 yr after one treatment with 3000 mg gonadotropin-releasing hormone immunocontraceptive (GonaCon) compared to a similar group of naturally infected B. abortus–positive bison cows not treated with GonaCon. In each of the 5 yr, GonaCon-treated cows produced fewer offspring in relation to number of cows than the nontreated cows. Fisher's Exact test comparing offspring produced during the first reproductive season showed a significant difference between the two groups (P=0.0028). Differences in number of calves produced in GonaCon-treated and control groups were also noted in remaining years, but statistics were not applied because of data constraints. These data indicate that one treatment with GonaCon in brucellosis-seropositive female bison reduced pregnancies over five reproductive years. Thus, immunocontraception could potentially be used to manage brucellosis in affected herds. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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