| Abstrakt: |
A recent study conducted at the National Institute for Communicable Disease Control and Prevention in Beijing, China, explored the immunogenicity of a T-cell epitope-based antigen derived from Mycobacterium tuberculosis (MTB) called Rv2201-519. The researchers constructed a recombinant protein, Rv2201-519, and tested its ability to detect tuberculosis infection and stimulate an immune response in mouse models. The results showed that Rv2201-519 had promising sensitivity for detecting tuberculosis infection, although lower than a commercial diagnostic kit. The study suggests that Rv2201-519 could potentially be used in future studies for tuberculosis infection screening and vaccine development. [Extracted from the article] |
