Tianjin Medical University Eye Hospital Researchers Release New Study Findings on Glaucoma (Neuroprotective effects of acteoside in a glaucoma mouse model by targeting Serta domain-containing protein 4).

Zdroj: Genomics & Genetics Weekly; 4/12/2024, p2467-2467, 1p
Abstrakt: Researchers from Tianjin Medical University Eye Hospital have conducted a study on the therapeutic effects of acteoside in a glaucoma mouse model. The study used proteomics to compare the differentially expressed proteins in mice. The results showed that acteoside treatment led to decreased intraocular pressure, improved wave amplitudes, thicker retina, and increased cell numbers in the ganglion cell layer. The study suggests that acteoside may protect retinal ganglion cells from damage by downregulating the expression of Serta domain-containing protein 4 (Sertad4), and could potentially be used in glaucoma treatment. [Extracted from the article]
Databáze: Supplemental Index