| Autor: |
SKALSKA, M., MYŚLIWIEC, A., MICHALAK, A., CHRZANOWSKI, J., LEJK, A., JASTRZĘBSKA, J., RADZIMIŃSKI, Ł., LOPEZ-SANCHEZ, G. F., MYŚLIWIEC, K., JASTRZĘBSKI, Z., WEISS, K., KNECHTLE, B. |
| Zdroj: |
European Review for Medical & Pharmacological Sciences; Mar2024, Vol. 28 Issue 5, p1987-1997, 11p |
| Abstrakt: |
OBJECTIVE: The main purpose of this study was to characterize the determinants of metabolic changes in young type 1 diabetes (T1DM) and to determine glycemic variability during low and high-intensity exercise. PATIENTS AND METHODS: 20 young male T1DM patients were divided into two subgroups characterized by levels of glycated hemoglobin (HbA1c): HbA1c<7.3% (better HbA1c subgroup, n=10) and with levels HbA1c>7.3% (worse HbA1c subgroup, n=10). All participants performed a maximal oxygen uptake test and two efforts of various intensities (45 minutes of aerobic exercise and 30 minutes of mixed aerobic-anaerobic intensity exercise). Continuous glucose monitors (CGM) were used to control the glucose concentration. RESULTS: Changes in biomarkers describing the metabolic response were similar in both groups. A comparison of applied efforts exhibited that maximal capacity effort resulted in the highest values of blood glucose (BG) at the end (150.9-160.6 mg/dl) and 1 hour after the exercise (140.2-161.3 mg/dl). BG concentration before, during, 1 hour, and 24 hours after each exercise was insignificantly higher in the worse Hb1Ac group. CONCLUSIONS: HbA1c levels are insufficient to confirm whether the applied effort is performed in acceptable glycemic values. The CGM monitors allow for precise control of BG variations and accurate planning of physical activity by adjusting the insulin and carbohydrate consumption dose [ABSTRACT FROM AUTHOR] |
| Databáze: |
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