| Autor: |
Menshchikov, Konstantin, Menshchikov, Mikhail, Yurasov, Dmitry, Artamonov, Anton |
| Zdroj: |
Arab Journal of Urology; Apr2024, Vol. 22 Issue 2, p96-101, 6p |
| Abstrakt: |
As available data on implantation-related infections is contradictory, the aim was to identify the predictors of penile prosthesis infection. We performed an umbrella review and meta-analysis including systematic reviews with extractable data. Literature search was done in two databases: PubMed and Google Scholar. The participants were males with erectile dysfunction regardless of etiology who underwent penile implant surgery. Using a standardized form, three trained researchers reviewed each reference (systematic review) by title and abstract. The meta-analysis was performed using Review Manager 5.4.1 (RevMan® 5.4.1). A total of 78 systematic reviews were identified with the search strategies. Of these, 35 duplicates were removed. Thirty-seven full-text reviews were then excluded after revision. Six systematic reviews with a total of 271,226 patients (156,553 patients in the study group and 114,673 patients in the control group) were included in the meta-analysis. The analysis identified various predictors of adverse outcomes (infection). Among them were glycated hemoglobin (HbA1c) and different characteristics of penile implants. The systematic review and meta-analysis revealed significant risk factors/predictors of penile prosthesis infection: glycated hemoglobin levels; reoperation, and two predictors associated with the type of penile prosthesis. The weighted mean HbA1c levels of patients with and without infections were 8.37% and 7.17% respectively. The OR was as follows: first surgery/revision OR 0.36 (95% CI 0.29–0.45); antibiotic-coated/non-coated prosthesis OR 0.47 (95% CI 0.31–0.72); malleable/inflatable prosthesis OR 3.51 (95% CI 1.41–8.74). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
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