The double product breakpoint as predictor of stress and the correlation between IL-12 and biomarkers in athletes.

Autor: LUÍS PRAMPERO, SÉRGIO, OLIVEIRA GONÇALVES, LUIS CARLOS, DUTRA MORAIS MOURÃO, NÁDIA RAQUEL, DE ABREU VERLI, MÁRCIO VINÍCIUS, LUZÍA FRANÇA, EDUARDO, HONORIO FRANÇA, ADENILDA, DE MAGALHÃES NETO, ANÍBAL MONTEIRO
Zdroj: Journal of Physical Education & Sport; Feb2024, Vol. 24 Issue 2, p456-463, 8p
Abstrakt: Immunometabolism emerges as the target for future research in health and exercise sciences. The impact caused by a treadmill running test on different biomarkers, changes in the cardiovascular system, and the correlation between IL-12 and performance. Ten male high-performance athletes performed using a gas analyzer, and the treadmill exercise protocol was progressively increased until exhaustion. The athletes ran an average distance of 3 km, characterized by a gradual load increase in stages until voluntary exhaustion. Thus, the initial speed was 10 km/h with an increment of 1 km every 400 meters. Correlation of 1.0 (P=0.00278) between IL-12 and VO2 in the respiratory compensation time and of 0.943 (P=0 .0167) between pre-exercise IL-12 and the time to reach maximal effort, with the same correlation and P-value between pre-exercise IL-12 and the distance covered, and pre-exercise IL-12 and the test time. Post-exercise IL-12 presented a correlation of 0.9 (P=0.0167) with the heart rate of the respiratory compensation point. A breakpoint for both the double product and heart rate was observed between minutes 2 and 3 of the test, both measurements being more acute than the anaerobic threshold and the respiratory compensation point, and even that breakpoint for systolic blood pressure. The average percentage change in heart rate and the double product obtained the same value (213%). The heart rate and the double product breakpoint are sensitive and acute markers of stress level, and the production of IL-12 depends on the intensity and duration of the exercise, which may correlate with performance. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index