Tricuspid regurgitation burden following transcatheter aortic valve replacement requiring early pacemaker implantation.

Autor: Moubarak, Ghadi, Lanfear, Allison T., Hamandi, Mohanad, Aldrich, Allison I., Van Zyl, Johanna S., Banwait, Jasjit K., Bomar, Jaccallene V., Chang, Soohyun A., Wang, Zuyue, Mack, Michael J., Szerlip, Molly I., Grayburn, Paul A.
Zdroj: Baylor University Medical Center Proceedings; Mar2024, Vol. 37 Issue 2, p205-209, 5p
Abstrakt: Conduction abnormality requiring the implantation of a permanent pacemaker (PPM) is a well-known and clinically important complication of transcatheter aortic valve replacement (TAVR). However, PPM implantation may result in lead-associated tricuspid valve regurgitation (TR). This study sought to determine the incidence and progression of TR following PPM implantation after TAVR. This was a retrospective review of all echocardiograms of patients who underwent PPM following TAVR at the Baylor Scott & White hospitals from 2012 to 2021. The primary endpoint was TR progression at 30 days and 1 year. A subanalysis comparing the change in TR progression between small and large TAVR devices was also conducted. Secondary outcomes included all-cause death at 30 days and 1 year. Out of the 2744 patients who underwent TAVR between April 2012 and August 2021, 177 patients (6.5%) subsequently received a new PPM. There was a statistically significant progression of TR at 1-year follow-up (McNemar's P value = 0.02). TR progression rates were comparable between the small and large valve groups at 1-year follow-up (4% vs 11%, P = 0.09, respectively). In this single healthcare system study, we demonstrated a significant progression of TR in patients with PPM post TAVR at 1 year. [ABSTRACT FROM AUTHOR]
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