Belgorod National Research University Researchers Highlight Research in Pharmacology (Neuroprotective properties of Na+/H+-exchanger isoform-1 inhibitor in experimental POAG).

Zdroj: Genomics & Genetics Weekly; 2/2/2024, p236-236, 1p
Abstrakt: A recent report from Belgorod National Research University highlights the neuroprotective properties of a Na+/H+-exchanger isoform-1 inhibitor in experimental primary open-angle glaucoma (POAG). Glaucoma is a leading cause of irreversible vision loss worldwide, and the study aimed to find ways to prevent the death of retinal neurons. The research was conducted on male Wistar rats, and the results showed that the inhibitor had a positive effect on ophthalmoscopic manifestations, electroretinogram amplitude, and gene expression related to apoptosis and neuroprotection. The findings suggest that further investigation of the inhibitor's potential against other retinal diseases is promising. [Extracted from the article]
Databáze: Supplemental Index