| Abstrakt: |
This study aimed to investigate the circulating levels of adiponectin and leptin levels and their association with fat mass, and lipid and glycaemic profiles in sedentary middle-aged adults without diabetes. Forty middle-aged sedentary adults (82.5% women; 53.4 ± 7.18 years old; BMI: 27.4 ± 3.9 kg/m2) took part in this study. Anthropometric measures including body mass, stature, waist circumference, and body mass index (BMI) were measured. Fat mass was determined by bioimpedance. Fasting blood samples were collected to determine adipokines and lipid and glycaemic profile outcomes. Pearson and Spearman's correlations were used to determine the associations between variables. Our results suggested that leptin is positively associated with BMI, waist circumference, fat mass, glucose, HbA1c (%), and total cholesterol. Regarding adiponectin levels, we found a negative association with BMI and triglycerides and a positive association with HDL-C levels. No significant associations were observed between adiponectin and glycaemic profile outcomes. Adiponectin/leptin ratio showed to be associated negatively with BMI, waist circumference, fat mass, fasting glucose, and triglycerides. This study has important clinical and public health implications supporting the importance of adopting a healthy lifestyle to maintain satisfactory levels of leptin and adiponectin, and consequently, a normal glycaemic and lipid profile. [ABSTRACT FROM AUTHOR] |
