A case of extramedullary multiple myeloma in the oral cavity.

Autor: Kaneko, Kotaro, Ogawa, Takashi, Minami, Sakura, Fujii, Yuko, Ikehata, Naoki, Chikazu, Daichi
Zdroj: Journal of Oral & Maxillofacial Surgery, Medicine & Pathology; Mar2024, Vol. 36 Issue 2, p227-229, 3p
Abstrakt: Cases of extramedullary multiple myeloma occurring in the oral cavity are rare. Herein, we present a unique case of extramedullary disease occurring twice in the oral cavity. A 72-year-old woman was diagnosed with multiple myeloma and was undergoing melphalan and prednisone therapy, along with thalidomide. The patient visited our hospital with a complaint of swelling of the left mandibular gingiva and an outward mass located on the buccal side of the left mandibular second molar. Radiographic and computed tomography examinations showed no bone resorption disease. Biopsy was performed for a definitive diagnosis, which confirmed extramedullary multiple myeloma. Radiation therapy was administered, and the lesion disappeared after 2 months. However, 2 months thereafter, a tumor appeared in the upper right maxillary gingiva, which disappeared following another round of radiation therapy. Subsequently, an extramedullary tumor developed systemically. The patient died due to poor management of the underlying disease. The development of extramedullary tumors is associated with a low survival rate, which should be given crucial consideration in treatment decisions. [ABSTRACT FROM AUTHOR]
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