| Autor: |
Medan, Ș., Andraș, I., Telecan, T., Giurgiu, L., Tișe, A., Berindean, A., Medan, P., Stanca, D. V., Crișan, N. |
| Předmět: |
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| Zdroj: |
Romanian Journal of Urology; 2022, Vol. 21 Issue 1, p36-46, 11p |
| Abstrakt: |
Introduction and Objectives. COVID-19 had a major impact on medical practice starting with 2019. Initially believed to be only a pneumonia with flu like symptoms gradually several other symptoms affecting the gastrointestinal tract, central nervous system, cardiovascular system, liver, bone marrow and kidney, were observed to be common among COVID-19 patients. It is supposed that SARS-CoV-2 virus interaction with the ACE receptors is responsible for the various symptomatology. We aimed to see if there was a difference in the acute phase of the infection and 3 months after discharge regarding the urological symptoms and also to find correlations among urological symptoms and other disease characteristics. Materials and Methods. Data from 429 COVID-19 patients admitted in our hospital between October 2020 and April 2021, were gathered during the acute phase of the disease respectively 3 months after discharge. At 3 months we were able to contact 355 of them. We then analyzed the frequency of acute urinary retention, lower urinary tract symptoms (urgency, pollakiuria, dysuria, burning sensation at micturition) sexual disfunction, stress incontinence. For symptoms quantification we used the scores of ISI, IPSS and IIEF. We performed a multivariate analysis to observe the correlation between the symptoms and scores and disease characteristics or treatments received. Results. Most of the patients admitted presented with a severe form of the disease. According to the current guidelines they received antiviral treatment (90.4%), corticosteroid therapy (95.3%) and 36.8% required insulin therapy. Urinary tract infection was found in 5.5% of patients and microscopic hematuria was identified in 5.36% of patients. A correlation with a p of 0.05 was identified between the need of insulin therapy (IT) during hospitalization and the IIEF score, dysuria and a positive correlation with a p of 0.001 between burning sensation at micturition and IT. Also the International Thoracic Scoring System (TSS) score received by patients at CT scan was statistically significant correlated with the presence of stress urinary incontinence (p = 0.04). Urological symptoms did not differ significantly at 3 months after discharge. Conclusions. We observed a correlation between the need of IT and LUTS and also between TSS and stress urinary incontinence. There is no statistically significant difference among symptoms in the acute phase of the infection and 3 months afterwards. [ABSTRACT FROM AUTHOR] |
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