| Abstrakt: |
A recent study conducted at Chiang Mai University in Thailand explored the effects of Sophora exigua root extract on non-small cell lung cancer (NSCLC) using an in vitro model. The researchers found that the ethyl acetate fraction of the extract exhibited significant anti-inflammatory properties, inhibiting the production of cytokines from NSCLC cells. The active compounds in this fraction, exiguaflavanone A and exiguaflavanone B, were found to inhibit the proliferation, migration, and invasion of NSCLC cells. Additionally, these compounds suppressed the activation of the NLRP3 inflammasome pathway, suggesting that targeting this pathway could be a promising therapeutic approach for NSCLC. [Extracted from the article] |
