Pleural mesothelioma in a California sea lion (Zalophus californianus).

Autor: Yuki TAKAMI, Miyuu TANAKA, Masahiro MORITA, Takaya MARUNO, Naohiro ANAI, Tsubasa SUDO, Chiho KEZUKA, Takeshi IZAWA, Jyoji YAMATE, Mitsuru KUWAMURA
Předmět:
Zdroj: Journal of Veterinary Medical Science; 2023, Vol. 85 Issue 9, p1030-1033, 4p
Abstrakt: A 25-year-old female California sea lion (Zalophus californianus) reared in an aquarium died following a history of anorexia, lethargy, abnormal protrusion of the skin, and oral respiration. At necropsy, multiple yellowish-white nodules with diameters of 0.1-0.5 cm were disseminated in the thoracic cavity and lungs. Histopathologically, the nodules were continuous with normal mesothelium and were characterized by the proliferation of spindle-shaped to polygonal neoplastic cells with prominent atypia. The neoplastic cells exhibited diffuse, strong staining for vimentin and partial, weak to moderate staining for cytokeratin AE1/AE3. Based on these findings, the lesions were diagnosed as pleural mesothelioma. This study reports the first case of pleural mesothelioma in California sea lion. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index