Fusobacterium nucleatum and Prevotella in women with periodontitis and preterm birth.

Autor: Martins Lima, Karyne, Coelho Alves, Claudia Maria, Branco Vidal, Flávia Castello, Gomes-Filho, Isaac Suzart, Costa e Costa, Jéssica, Della Coletta, Ricardo, Pinheiro Rodrigues, Vandilson, Ferreira Lopes, Fernanda
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Zdroj: Medicina Oral, Patologia Oral y Cirugia Bucal; Sep2023, Vol. 28 Issue 5, pe450-e456, 7p
Abstrakt: Background: Studies try to explain the hypothesis that maternal periodontitis may be associated with preterm birth. Material and Methods: This is a case-control study with 120, 40 cases (gestational age <37 weeks) and 80 controls (gestational age =37 weeks), that were submitted to the clinical periodontal examination and subgingival biofilm collection. Bacterial DNA of subgingival biofilm was performed and processed by qPCR. Results: Periodontitis was statistically significant in the Case group (35%) when compared to the Control group (11.2%) and Gingival Bleeding Index (GBI), sites with PS = 4mm and sites with CAL = 5mm were statistically higher in the Case group (p < 0.05). The proportions of Pi (p = 0.026) and Fn (p = 0.041) of subgingival biofilm were higher in the Case group. A greater number of sites with PS = 4mm (r = -0.202; p = 0.026) and CAL = 5mm (r = -0.322; p < 0.001) were correlated to lower gestational age. Conclusions: Periodontitis, preterm delivery, and/or low birth weight may have a possible relationship based on clinical parameters and the ratio of Pi and Fn at periodontal sites. [ABSTRACT FROM AUTHOR]
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