| Abstrakt: |
This paper presents a solution method for the inverse problem in which an optical pulse is radiated to a biological medium and the optical parameters of the medium are estimated. The method in this paper is based on the FTDT method which the authors have previously formulated. It can be applied to estimation of the optical parameters in a biological object even if the optical parameters are nonhomogeneously distributed. First, the proposed method is applied to a homogeneous scattering medium and the validity of the method is verified. Then, the method is applied to a simplified human head model with a three-layered structure, composed of skull, gray matter, and white matter. The subset of optical parameters is defined on the basis of the independence of the differential amplitude, which represents the contribution of the optical parameters of the human head to the backscattered waveform, and the time waveform, which is obtained by differentiating the backscattered waveform with respect to each optical parameter. It is shown that the optical parameters of all three layers can be identified with an accuracy of ±1% by successively determining the optical parameters composing the subset. © 2005 Wiley Periodicals, Inc. Syst Comp Jpn, 36(7): 64–72, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/scj.20134 [ABSTRACT FROM AUTHOR] |
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