| Abstrakt: |
The most commonly used cancer treatments were surgical therapy, radiotherapy, and/or chemotherapy, all of which have significant side effects that can reduce a patient's quality of life. Flavonoids, an antioxidant thought to be involved in tumor growth and apoptosis, are found in ant nest plants, also known as Myrmecodia pendans. The goal of this study was to see how effective ant nest flavonoids are at inducing apoptosis in cancer cells and providing physiological death mechanisms. The study was a review of the literature within articles that met the inclusion criteria: experimental controlled trial of ant nest plant extract biological therapy and its effect on cancer cell apoptosis activity. Search engines such as Google Scholar, ProQuest, ScienceDirect, and Wiley Online Library were used with strategic keywords. The final review included 7 of the 4869 articles discovered through database searching. Flavonoids, tannins, polyphenols, and glycosides, all of which have antioxidant properties, were discovered in ant nests. Flavonoids have the ability to influence apoptotic pathway signalling via two mechanisms: Suppressing pro-apoptotic proteins and activating anti-apoptotic proteins and caspases. Ant nest extract has been shown to be a promising alternative in cancer treatment. [ABSTRACT FROM AUTHOR] |
