| Autor: |
Adam, Mardiana, Achmad, Harun, Tanumihardja, Maria, Oktawati, Sri, Ramadhan, Sitti Raoda Juanita, Afriani, Adhawanty, Masyta, Nur |
| Předmět: |
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| Zdroj: |
Journal of International Dental & Medical Research; 2023, Vol. 16 Issue 1, p117-123, 7p |
| Abstrakt: |
Periodontitis is a disease that damages the periodontal tissue and can cause tooth loss. In recent years there has been an interest in carrying out regenerative efforts as periodontal therapy. Bonegraft derived from natural materials is the current choice because of the limitations of the available synthetic bonegrafts. The aim of this study was to analyze the effect of golden sea cucumber on the increase of BMP2 and Osteoprotegrin on bone regeneration. This research is a laboratory experimental study with male guinea pigs as the subject. The number of samples is 30 guinea pigs. After 14 and 21 days sacrificed was performed for immunohistochemical examination. The expression of BMP2 and OPG had a significant difference between the sea cucumber group and the positive control group. It can be concluded that bonegraft from golden sea cucumbers has a mechanism as bonegraft material so that it can be used as an alternative material in regenerative therapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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