Inducing murin CCR5-downregulating antibodies prevents HIV infection.

Zdroj: AIDS Vaccine Week; 3/21/2005, p5-6, 2p
Abstrakt: This article cites a study conducted by researcher Claudia Barassi and colleagues, published in the journal "Microbiologica," according to which induction of murin CCR5-downregulating antibodies that offers a new prospect against HIV infection. Researchers report that natural resistance to HIV is widely growing in humans. An example of an extremely efficacious resistance is represented by exposed seronegative (ESN) subjects, that is individuals who, despite repeated sexual and/or parenteral exposure to HIV, remain seronegative and apparently uninfected. A small group within ESN produces anti-CCR5 antibodies, which cause antigen down-modulation and a CCR5 minus phenotype.
Databáze: Supplemental Index