Safety and Effectiveness of Moderate Sedation With Ketamine and Midazolam Combination in Vascular and Interventional Radiology Procedures.

Autor: Alahmad, Mohammed Abdullah, Alhussaini, Abdulmohsen Ahmed, Alghamdi, Abdullah Saed, Alzahrani, Mohammed, Alomaim, Mohammed Mubarak, Othman, Khalid, Arabi, Mohammad
Zdroj: Journal of Radiology Nursing; Jun2023, Vol. 42 Issue 2, p175-177, 3p
Abstrakt: Ketamine is known to induce dissociative anesthesia while maintaining airways and hemodynamics. The aim of this study is to assess the safety and effectiveness of moderate sedation using a mixture of ketamine and midazolam in vascular and interventional radiology procedures. Patients received aggregate doses of the mixture of 50 mg ketamine and 2.5 mg midazolam, diluted in 10 mL of normal saline. The starting dose was 10 mg of ketamine followed by 10–20 mg increments after 10–15 minutes. Side effects were observed in 5 patients. No cardiovascular or respiratory complications were encountered. The mean lowest Ramsay score during the procedure was 1.9 ± 0.5 (range, 1–3) and the mean highest Ramsay score during the procedure was 2.7 ± 0.7 (range, 2–5). Aldrete score was recorded in 72 patients with a mean of 9.7 (range, 7–10). Ketamine and midazolam combination appears to be effective in providing adequate moderate sedation and analgesia. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index