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Keywords: Anthelmintics; Antimicrobials; Antinematodal Agents; Drugs and Therapies; Health and Medicine; Organic Chemicals; Pharmaceuticals; Piperazine Therapy; Urea EN Anthelmintics Antimicrobials Antinematodal Agents Drugs and Therapies Health and Medicine Organic Chemicals Pharmaceuticals Piperazine Therapy Urea 787 787 1 05/22/23 20230526 NES 230526 2023 MAY 26 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Researchers detail new data in antimicrobials. Antimicrobials, Antinematodal Agents, Anthelmintics, Drugs and Therapies, Health and Medicine, Organic Chemicals, Pharmaceuticals, Piperazine Therapy, Urea Compounds N-(4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl) phenyl) cyclobutanecarboxamide (9 g), 1-cyclopropyl-3-(4-(4-(5-fluoropyrimidin-2-yl) piperazin-1-yl) phenyl) urea (7c) and 1-cyclobutyl-3-(4-(4-(5-fluoropyrimidin-2-yl) piperazin-1-yl) phenyl) urea (7d) exhibited strong antimicrobial activity against K. pneumonia, with an IC50 of 27.1, 32.4, and 32.4 mg/ml, respectively. [Extracted from the article] |
