Lymphomas affecting the Sublingual glands: A clinicopathological study.

Autor: Araújo G., Ribeiro de, A. L., Morais-Perdigão, J. M., Aguirre Urizar, H. A., Rebelo Pontes, C., Dantas Soares, F., Paiva Fonseca
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Zdroj: Medicina Oral, Patologia Oral y Cirugia Bucal; 2023 Supplement, Vol. 28, pS18-S19, 2p
Abstrakt: Introduction: Lymphomas affecting the sublingual glands are extremely rare, and few case reports are currently available, avoiding a better understanding of this clinical presentation. Objectives: The current study aims to describe the clinicopathological and microscopic features of a series of lymphomas involving the sublingual glands. Material and Methods: All cases diagnosed in four pathology services were assessed, and the formalin-fixed paraffin-embedded tissue blocks were retrieved for diagnosis confirmation. Clinical data were obtained from the patient’s medical files. Results: We obtained seven cases of lymphomas in the sublingual glands representing two follicular lymphomas, two diffuse large B cell lymphomas not otherwise specified (DLBCL NOS), two MALT lymphomas, and one mantle cell lymphoma. In all cases, the tumor cells infiltrated the glandular parenchymal, although in two of them, the neoplastic cells were located more superficially and permeated the glandular acini and ducts. Clinically, the tumors presented as asymptomatic nodules, and one patient (affected by DLBCL NOS) died, while the other cases remained alive at the last follow-up. Conclusions: Lymphomas affecting the sublingual glands are usually of the mature B cell lineage, usually representing lowgrade subtypes, and may clinically resemble other more common lesions in the floor of the mouth, like salivary gland tumors. [ABSTRACT FROM AUTHOR]
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