The modified systemic inflammation score is a predictor of ICU admission of COVID-19 patients.
| Autor: | Metin, Damla Anbarli, Metin, Hamdi, Atiş, Şeref Emre |
|---|---|
| Předmět: |
INTENSIVE care units
C-reactive protein COVID-19 CONFIDENCE intervals HEMOGLOBINS HOSPITAL emergency services INFLAMMATION CROSS-sectional method RETROSPECTIVE studies MANN Whitney U Test QUANTITATIVE research RISK assessment SERUM albumin COMPARATIVE studies HOSPITAL care DESCRIPTIVE statistics LEUKOCYTE count PLATELET count CHI-squared test LOGISTIC regression analysis ODDS ratio DATA analysis software MONOCYTE lymphocyte ratio LYMPHOCYTE count CREATININE ASPARTATE aminotransferase ALANINE aminotransferase MEDICAL needs assessment |
| Zdroj: | Journal of Acute Disease; Jan2023, Vol. 12 Issue 1, p18-22, 5p |
| Abstrakt: | Objective: To evaluate the effect of the modified systemic inflammation score (mSIS) on prognosis in patients diagnosed with COVID-19. Methods: In this retrospective cross-sectional study, 181 patients were selected and divided into two groups: patients with and without admission to the intensive care unit (ICU). An albumin level of =4.0 g/dL and lymphocyte-to-monocyte ratio (LMR) of =3.4 was scored 0, an albumin level of <4.0 g/dL or LMR of <3.4 was scored 1, and an albumin level of <4.0 g/dL and LMR of <3.4 was scored 2. Results: A total of 242 COVID-19 positive patients were initially included in this study. Of these patients, 61 were excluded and 181 patients remained. Among the 181 participants, 94 (51.9%) were female, and the median age was 61 (51, 75) years. The mSIS scale ranged from 0 to 2. After analysis, the median score was 0 (0, 0) in the non-ICU group and 2 (0, 2) in the ICU group (P<0.001). The median white blood cell, lymphocyte counts, and albumin levels were lower in the ICU group (P<0.001, P<0.001, and P<0.001, respectively). In logistic regression analysis lymphocytopenia (OR=5.158, 95% CI=1.249-21.304, P=0.023), hypoalbuminemia (OR=49.921, 95% CI=1.843-1 352.114, P=0.020), AST elevation (OR=3.939, 95% CI=1.017-15.261, P=0.047), and mSIS=2 (OR=5.853, 95% CI=1.338-25.604, P=0.019) were identified as independent predictors of ICU admission. Conclusion: The mSIS can be used as an independent parameter for establishing the intensive care needs of patients with COVID-19. [ABSTRACT FROM AUTHOR] |
| Databáze: | Supplemental Index |
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