Characteristics and Outcomes of Hospitalized Geriatric Patients with COVID-19 Infection in Taiwan.

Autor:	Hsin-Pei Chung, Kuo-Lun Wu, Chang-Yi Lin, Yen-Hsiang Tang, Chao-Hsien Chen, Jou-Chun Wu, Yen-Ting Chen, Kuan-Chih Kuo, Wen-Kuei Chang
Předmět:	LENGTH of stay in hospitals ALBUMINS REVERSE transcriptase polymerase chain reaction HYPERTENSION CHRONIC kidney failure COVID-19 CONFIDENCE intervals AGE distribution FERRITIN MULTIVARIATE analysis LOG-rank test RETROSPECTIVE studies ACQUISITION of data CALCITONIN TERTIARY care HEALTH outcome assessment MANN Whitney U Test TREATMENT effectiveness COMPARATIVE studies HOSPITAL mortality ARTIFICIAL respiration T-test (Statistics) HOSPITAL care of older people MEDICAL records OBSTRUCTIVE lung diseases DESCRIPTIVE statistics ELECTRONIC health records LOGISTIC regression analysis TUMORS BODY mass index DATA analysis software ODDS ratio FIBRIN fibrinogen degradation products CREATININE
Zdroj:	International Journal of Gerontology; Jul2022, Vol. 16 Issue 3, p207-212, 6p
Abstrakt:	Background: Geriatric patients with COVID-19 have had poor clinical outcomes globally, especially during the first wave of the pandemic. In Taiwan, the first wave of the COVID-19 pandemic occurred from May to July 2021. This retrospective study aimed to compare the characteristics and outcomes between geriatric and younger patients with COVID-19 infection. Methods: A total of 257 confirmed COVID-19 cases who were hospitalized from May to June 2021 were included. Their characteristics and outcomes, including in-hospital mortality, use of mechanical ventilation, and hospital stay, were collected for analysis. Results: There were 98 elderly patients (aged ≥ 65 years, median, 72.5 (interquartile range, 69.0-78.0) years) and 159 younger patients (aged < 65 years, median 55.0 (46.0-60.0) years). The elderly patients had a significantly higher Charlson comorbidity score (4.0 (3.0-5.0) vs. 1.0 (1.0-2.0), p < 0.001), and significantly higher D-dimer, procalcitonin, ferritin, and creatinine levels, but lower albumin level than the younger patients. The elderly group also had higher in-hospital mortality (7.1% vs. 1.9%, p < 0.05), were more likely to develop severe disease (83.7% vs. 67.9%, p < 0.01), and had a longer hospital stay (15.0 (11.0-23.0) vs. 12.0 (9.0-16.5) days, p < 0.001). Nevertheless, the elderly patients did not have a higher risk of using high-flow nasal cannulas (17.3% vs. 15.1%, p = 0.63) or mechanic ventilation (23.5% vs. 17.0%, p = 0.20). Conclusion: Elderly COVID-19 patients had significant higher risks of severe disease, mortality, and longer duration of hospitalization, possible due higher rates of comorbidities and pro-inflammatory status. [ABSTRACT FROM AUTHOR]
Databáze:	Supplemental Index
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