| Autor: |
G., Abhishek M., K., Rajeshwari, N., Karibasappa G., Basri, Rehana, Patil, Santosh R., Alam, Mohammad Khursheed |
| Zdroj: |
International Medical Journal; Oct2022, Vol. 29 Issue 5, p296-299, 4p |
| Abstrakt: |
Background: Bladder neoplasms contribute to significant mortality and morbidity that are more disabling and lethal. Hence early and accurate histomorphological diagnosis with grading and staging helps in early management thus having better prognosis of bladder neoplasms. Objective: The present study aimed to study the clinico-histomorphological features of bladder lesions with special emphasis on grading and staging of the bladder neoplasms. Materials and Methods: The present study is a descriptive type carried out over a period five years from June 2015-June 2020 at a Multispecialty private hospital Trident, Bangalore. All patients who visited to urology outpatient department with lower urinary tract symptoms and obstructive bladder symptoms were subjected to cystoscopy. The detailed clinico-histomorphological features were studied using World Health Organization (WHO) 2016 histological grading system and Tumour, lymphnode and Metastasis (TNM) staging and thus used in classifying the bladder neoplasms. Results: Among 331 cystoscopic biopsies received, neoplastic lesions constituted 63.4% of the cases. Among the neoplastic lesions, malignant lesions accounted for 89.52% of the cases. Among the malignant lesions, urothelial carcinoma (90.4%) was the commonest with high prevalence of high grade papillary urothelial carcinoma (58.85%) and invasive papillary urothelial carcinoma (84.34%). Conclusions: In our study we observed a high prevalence of bladder neoplasms. Clinically most of the patient with benign bladder neoplasms presented with lower urinary tract symptoms while malignant bladder neoplasms presented with haematuria. Majority of bladder tumours on cystoscopy was localized on the lateral wall of bladder. The gold standard histomorphology in adjunct to histochemical and immunohistochemistry helps in early, accurate grading and staging of bladder tumours thus helps in early management with better prognosis of the of bladder neoplasms. [ABSTRACT FROM AUTHOR] |
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