| Autor: |
Santos, Erison Santana Dos, Rodrigues-Fernandes, Carla Isabelly, Normando, Ana Gabriela Costa, Da Silva Guerra, Eliete Neves, Lopes, Marcio Ajudarte, Santos-Silva, Alan Roger, Leme, Adriana Franco Paes |
| Zdroj: |
Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Sep2022, Vol. 134 Issue 3, pe229-e229, 1p |
| Abstrakt: |
To assess the association between primary sites of salivary gland tumors (SGTs) and prognosis. Studies from 5 databases were assessed and a meta-analysis was performed using studies that presented 95% CI, hazard ratio (HR), and survival analysis. QUIPS (Quality in Prognosis Studies) was used to assess the methodological quality of included studies, and GRADE (Grading of Recommendation, Assessment, Development, and Evaluation) was used to assess the quality of evidence. Results from 46,361 patients showed that site had a prognostic effect on SGTs. Tumors involving minor salivary glands showed worse overall survival (HR = 1.60; 95% CI, 1.17-2.19; P =.003), disease-specific survival (HR = 1.63; 95% CI, 1.12-2.37; P =.01), and cause-specific survival (HR = 2.10; 95% CI, 1.72-2.55; P =.00001). Tumors from major salivary glands showed better recurrence-free survival (HR = 2.31; 95% CI, 1.77-3.02; P =.00001) and locoregional control of disease (HR = 2.66; 95% CI, 1.20-5.91; P =.02). Our results showed that the primary site of SGTs has an effect on survival and patient prognosis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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