| Autor: |
Tetsuya SHIMODA, Mika TANABE, Yuuki SHOJI, Takuya KANDA, Kouhei KISHIDA, Ai KISHIDA, Atsushi HASHIMOTO, Mako OTSUKA, Akina MIYAMOTO, Tomoko KAWAKITA, Wataru OSHITA, Reijiro HIRAO, Akihisa SUWA |
| Předmět: |
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| Zdroj: |
Journal of Veterinary Medical Science; 2022, Vol. 84 Issue 2, p251-256, 6p |
| Abstrakt: |
A cat was presented with depression and anorexia. The complete blood cell count (CBC) revealed non-regenerative anemia (PCV, 8.5%), marked thrombocytopenia (2,400/μl), and leukocytosis (32,090/μl). In the peripheral blood, proliferation of blast cells (85%; 27,276/μl) and basophils (7.7%; 2,460/μl) was observed. Bone marrow aspirate showed hyperplasia with 8.8% blasts and 90.2% basophils of all nucleated cells. The blast cells were negative for myeloperoxidase staining and positive for alpha-naphthol butyrate esterase staining, indicating the agranular blasts are monoblasts. Thus, acute monoblastic leukemia (M5a) with chronic basophilic leukemia was diagnosed. Basophils accounted for more than 40% of the bone marrow, and we diagnosed secondary basophilic leukemia. Secondary basophilic leukemia should be included in the differential list when abnormal basophil increases are observed in feline bone marrow. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
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