| Autor: |
Radion, Garaz, Paul-Gabriel, Borodi, Ioan Alin, Nechifor-Boilă, Ghirca, Veronica Maria, Daniel, Bălan, Orsolya, Mártha, Bogdan, Chibelean Călin |
| Předmět: |
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| Zdroj: |
Romanian Journal of Urology; 2020, Vol. 19 Issue 4, p16-21, 6p |
| Abstrakt: |
Introduction and Objectives. This study aimed to assess the incidence of pathological upstaging of renal tumors in relation to the surgical technique (radical/partial nephrectomy) or approach (laparoscopic/open) as well as its potential associations of clinical and/or pathological factors. Materials and Methods. We retrospectively reviewed patients who underwent any type of nephrectomy (radical/partial or open/laparoscopic) for renal tumors between January 2018 and December 2020. Among 175 eligible patients, 139 patients were available for our analysis. We conducted a comparative analysis according to clinical and pathological characteristics of two groups: upstaged group (n = 17) and the non-upstaged group (n = 122). Results. Pathological upstaging was found in 17 patients (12.23%) with a majority of pT3a (13 patients, 76%). Patients in the upstaging group exhibited a higher proportion of cT1b stage (65% (11) vs. 47% (57), p=0.01), pT3a stage (76% (13) vs. 14% (17), p <0.0001) as well as a higher Fuhrman grade (Grade 3 and 4) (47% (8) vs. 25% (30), p=0.001). Conclusions. Pathological upstaging occurred more frequently in patients with radical nephrectomy as well as in patients that benefited from open surgery. Tumor size and high Fuhrman grade were related to upstaging, exerting an influence on patient follow-up protocol. [ABSTRACT FROM AUTHOR] |
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