| Autor: |
Járdánházy, Anett, Járdánházy, Tamás |
| Předmět: |
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| Zdroj: |
Neurological Research; Feb 2022, Vol. 44 Issue 2, p104-111, 8p |
| Abstrakt: |
Objectives The present study aimed to compare the effectiveness of different provocation tests used for the study of the 'susceptibility to seizure' by quantitative electroencephalography (EEG) analysis. Methods Eight subjects with a history of a seizure-like disturbed consciousness participated in this preliminary study. A routine EEG was carried out with photic stimulation (eyes closed and after eyes open) at the beginning of the investigation. Some days later, a sleep-deprived EEG was recorded with the same protocol. Selected epochs (in eyes closed condition) after the stimulations were analysed with Point(wise) Correlation Dimension (PD2i) and Synchronization Likelihood (SL) methods. The results were compared to those obtained by similar analysis of the resting state (control) epochs with Wilcoxon Signed Rank Test (p ≤ 0.05). Results In our study, significantly lower grand mean PD2i and higher delta SL values were found in sleep-deprived state after stimulation with eyes closed compared to the control. Our results indicated a lower-dimensional, hypersynchronous state of the brain as a consequence of these combined provocations. Discussion This may correspond to a possible 'preictal' state of the brain. Accordingly, it is suggested that photic stimulation together with sleep deprivation seems to be more effective in provocation – especially when the stimulation was made with eyes closed. [ABSTRACT FROM AUTHOR] |
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