| Autor: |
Rajan, Kumar B., Weuve, Jennifer, Barnes, Lisa L., McAninch, Elizabeth A., Wilson, Robert S., Evans, Denis A. |
| Zdroj: |
Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2021, Vol. 17 Issue 12, p1966-1975, 10p |
| Abstrakt: |
Introduction: The estimate of people with clinical Alzheimer's disease (AD) and mild cognitive impairment provides an understanding of the disease burden. Methods: We estimated people with cognitive impairment using a quasibinomial regression model in 10,342 participants with cognitive test scores. Results: The 2020 US Census–adjusted prevalence of clinical AD was 11.3% (95% confidence interval [CI] = 10.7–11.9): 10.0% among non‐Hispanic Whites, 14.0% among Hispanics, and 18.6% among non‐Hispanic Blacks. We estimate that in 2020, 6.07 (95% CI = 5.75–6.38) million people were living with clinical AD, which increases to 13.85 (95% CI = 12.98–14.74) million in 2060, 423% higher among Hispanics, 192% higher among Blacks, and 63% higher among Whites. However, there are predicted to be more significant increases in later years among those over 85 and women compared to men. Discussion: The number of people with clinical AD will increase as the "baby boom" generation reaches older ages, exerting a strong upward influence on disease burden. [ABSTRACT FROM AUTHOR] |
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