The Ph Salivary Biomarker – is There a Difference Between Cleft and Non-Cleft Orthodontic Patients?

Autor: de Souza Schacher, Helena Reis, Lemos Rinaldi, Mariana, Azeredo, Fabiane, Deon Rizzatto, Susana Maria, Sasso Stuani, Maria Bernadete, de Menezes, Luciane Macedo
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Zdroj: Journal of International Dental & Medical Research; 2021, Vol. 14 Issue 3, p1014-1020, 7p
Abstrakt: Cleft lip and/or palate (CL/P) is one of the most common congenital malformations. In view of the important role of salivary pH and the scarcity of studies on this topic in patients with CL/P, the aim of this study was to analyze salivary pH in patients with and without CL/P undergoing orthodontic treatment with fixed appliances. The sample consisted of 45 patients wearing orthodontic appliances (20 boys and 25 girls; mean [SD] age, 15 [2.70] years), who were divided into 3 groups: control group (patients without CL/P, n = 15); CL/P group (patients with CL/P without oronasal communication, n = 15); and CL/P-O group (patients with CL/P with oronasal communication, n = 15). Saliva samples were collected and evaluated for pH by using indicator strips, with a reading scale ranging from 2.0 to 9.0. Data were tested for normality using the Shapiro-Wilk test, and results were compared by the Kruskal-Wallis test (p ≤ 0.05). The median pH was 7.5 in the control group, 7.0 in the CL/P group, and 6.5 in the CL/P-O group. Although there was no statistically significant difference among the 3 groups (p ≤ 0.05), the CL/P and CL/P-O groups tended to have lower and more scattered pH values than the control group. Salivary pH did not differ statistically between patients with and without CL/P wearing fixed orthodontic appliances. However, those with CL/P tended to have more acidic and scattered pH values. Further studies and trials involving a larger number of patients are important to clarify this issue. [ABSTRACT FROM AUTHOR]
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