| Autor: |
Kasumi SUDO, Manabu YAMADA, Mariko OCHIAI, Shoko IWAMOTO, Hajime SAKAKI, Chiho KUSHIDA, Maiko YAMASHITA, Atsushi YAMAMOTO, Takao NAGASAKA, Mikio OIDEMIZU, Akito SAITO, Kinya YAMAMOTO |
| Předmět: |
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| Zdroj: |
Journal of Veterinary Medical Science; 2021, Vol. 83 Issue 6, p990-993, 4p |
| Abstrakt: |
We evaluated the role of classical swine fever virus (CSFV) in the formation of button ulcers in the mucosa of the gastrointestinal tract. Histopathological and immunohistochemical analyses of pigs experimentally infected with a subgenotype 2.1 isolate of CSFV, which was isolated in Japan in 2019, revealed follicular necrosis in the submucosal mucosa-associated lymphoid tissue and herniation of crypts as factors that contribute to the development of button ulcers during CSFV infection. These findings indicate that CSFV induces follicular necrosis and is one of the causative agents of button ulcers in pigs. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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