Design, Synthesis, and Biological Evaluation of Retinoic Acid-Related Orphan Receptor γt (RORγt) Agonist Structure-Based Functionality Switching Approach from In House RORγt Inverse Agonist to RORγt Agonist.

Autor: Yukawa, Tomoya, Nara, Yoshi, Kono, Mitsunori, Sato, Ayumu, Oda, Tsuneo, Takagi, Terufumi, Sato, Takayuki, Banno, Yoshihiro, Taya, Naohiro, Imada, Takashi, Shiokawa, Zenyu, Negoro, Nobuyuki, Kawamoto, Tetsuji, Koyama, Ryokichi, Uchiyama, Noriko, Skene, Robert, Hoffman, Isaac, Chen, Chien-Hung, Sang, BiChing, Snell, Gyorgy
Zdroj: Journal of Medicinal Chemistry; 2/14/2019, Vol. 62 Issue 2, p1167-1179, 13p
Databáze: Supplemental Index