Discovery of TRPM8 Antagonist (S)‑6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine.
Autor: | Horne, Daniel B., Biswas, Kaustav, Brown, James, Bartberger, Michael D., Clarine, Jeffrey, Davis, Carl D., Gore, Vijay K., Harried, Scott, Horner, Michelle, Kaller, Matthew R., Lehto, Sonya G., Liu, Qingyian, Ma, Vu V., Monenschein, Holger, Nguyen, Thomas T., Yuan, Chester C., Youngblood, Beth D., Zhang, Maosheng, Zhong, Wenge, Allen, Jennifer R. |
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Zdroj: | Journal of Medicinal Chemistry; 9/27/2018, Vol. 61 Issue 18, p8186-8201, 16p |
Databáze: | Supplemental Index |
Externí odkaz: |