| Autor: |
Varadaraj, Priyadarshini, Gopalan, Sowmya, Nair, Aiswarya M., Marappa, Lakshmi, Rajendran, Vaasanthi, Pandurangan, Viswanathan, Madhavan, Sudha, Mani, Rajkumar, Bhaskar, Emmanuel |
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| Zdroj: |
Critical Care & Shock; 2021, Vol. 24 Issue 3, p130-134, 5p |
| Abstrakt: |
Real-world reports on outcomes of SARS-CoV- 2 infection using higher oxygenation targets along with steroid therapy are lacking. We conducted a retrospective study of patients requiring oxygen support following targets of oxygenation >95% along with steroid therapy and were divided into 3 groups. Group 1 with oxygenation through a nasal cannula or Hudson mask, Group 2 oxygenation with venturi system, and Group 3 with high flow nasal oxygen, 35-50 litres; non-invasive ventilation; mechanical ventilation. One hundred and eighteen patients (Group 1 74 patients, Group 2 15 patients, and Group 3 29 patients) were studied. The mean age was 55.7 years and most were male (n=77). One hundred and fourteen received dexamethasone or methylprednisolone. Most (88.3%) had at least one pre-existing chronic medical illness. Overall mortality was 22.8% (n=27). Group 3 had the highest mortality (75.9%) followed by Group 2 (26.7%) and Group 1 (1.35%). Our observation raises the query if a higher target of oxygenation for non-mechanical ventilated patients coupled with steroid therapy is beneficial. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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