Arterial spin labeling assessment of myometrial perfusion changes in patients with uterine fibroid and its impact on fertility.

Autor: Shady, Magda Mohammed Shawky, Gibreel, Ahmed Fathy El-said, Rashed, Dina Rashed Mohammed, Tharwat, Nehal
Zdroj: Egyptian Journal of Radiology & Nuclear Medicine; 5/6/2021, Vol. 52 Issue 1, p1-8, 8p
Abstrakt: Background: Fibroids are the most common uterine tumor in the reproductive age group. These tumors although benign, their relation to infertility is still controversial. The purpose of this study is to assess the fibroid impact on fertility using arterial spin labeling (ASL) technique. Results: This prospective study included 40 cases (30 female patients having uterine fibroid and 10 age- and sex-matched control cases). The 30 patients were divided according to their fertility into 2 subgroups: fertile (n = 15) and infertile (n = 15). All cases underwent pelvic magnetic resonance imaging (MRI) examination with ASL technique. The perfusion values were measured in the uterine walls, fibroids, and in the gluteus maximus muscle as control. ASL demonstrated non-significant difference in the perfusion between anterior and posterior uterine walls in the control cases and revealed significant difference in the perfusion between fibroid positive and fibroid negative uterine walls in patients with uterine fibroid (p value < 0.04). Perfusion values of the fertile and infertile subgroups showed no statistically significant difference. Conclusion: Arterial spin labeling is an evolving technique that can be used to evaluate the myometrial perfusion changes in patients with uterine fibroid without using contrast media. Uterine fibroids were associated with decreased perfusion but with no statistically significant impact on fertility. [ABSTRACT FROM AUTHOR]
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