Exploring the Role of Olfactory Marker Protein in Reproductive System: A Narrative Review.

Autor: Salmi, Ab Aziz, Rahimah, Zakaria
Zdroj: International Medical Journal; oct2020, Vol. 27 Issue 5, p577-580, 4p
Abstrakt: Background: Olfactory marker protein (OMP) is a key marker of mature olfactory receptor neurons (ORNs) in vertebrates. The expression of OMP has also been mapped in non-olfactory tissues such as the bladder, colon, pancreas, pituitary gland, and thyroid gland. Objectives: Immunolabeling of OMP has been observed in a small population of neurons in higher brain regions of rodents such as in the hypothalamus and amygdala. However, the involvement of OMP in the brain function is poorly understood. Method: This review of the literature focused on the role of OMP in the reproductive system. Conclusion: Interestingly, OMP is essential in normal production and secretion of prolactin. Also, OMP plays a role in mother preference as well as reproductive behaviours. Therefore, understanding its role in the brain can invoke novel pathways of the reproductive system. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index