Isolated Heavy Resistance Training or Combined with Aerobic Training Improves Strength Gain, Cardiac Remodeling and Functional Capacity in Healthy and Heart Failure Rats.

Autor: Pereira Alves, Jadson, Barcos Nunes, Ramiro, da Cunha Ferreira, Daniele, Potrick Stefani, Giuseppe, Boemo Jaenisch, Rodrigo, Dal Lago, Pedro
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Zdroj: Journal of Exercise Physiology Online; Aug2020, Vol. 23 Issue 4, p146-165, 20p
Abstrakt: The purpose of this study was to evaluate the impact of high-intensity resistance training (RT) isolated or combined with continuous aerobic training (CAT) on cardiac remodeling and left ventricular dysfunction in healthy and heart failure (HF) rats. Forty-one male Wistar rats were divided into: (a) sedentary sham; (b) resistance training sham; (c) combined exercise sham; (d) sedentary HF; (e) resistance training HF; and (f) combined exercise HF. Trained animals were subjected to a high-intensity RT protocol 3 times·wk-1, 75 to 85% of one repetition maximum (1RM) for 8 wks. Sham and HF trained groups showed the same responsiveness to muscle strength gain, improved functional capacity, as well as the attenuation of left ventricular end-diastolic pressure (LVEDP) and collagen volume fraction (CVF) in the HF groups subjected to RT protocols. Total volume of sets and repetitions showed a close relationship with attenuated LVEDP and the volume of repetitions influenced the reduction of CVF in HF rats. Our results suggest that the isolated RT and combined training can play an important role in cardiac function in animals with HF and the magnitude of responses to muscular strength gains are similar between healthy and HF rats. [ABSTRACT FROM AUTHOR]
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