Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models.

Autor: Lücking, Ulrich, Wortmann, Lars, Wengner, Antje M., Lefranc, Julien, Lienau, Philip, Briem, Hans, Siemeister, Gerhard, Bömer, Ulf, Denner, Karsten, Schäfer, Martina, Koppitz, Marcus, Eis, Knut, Bartels, Florian, Bader, Benjamin, Bone, Wilhelm, Moosmayer, Dieter, Holton, Simon J., Eberspächer, Uwe, Grudzinska-Goebel, Joanna, Schatz, Christoph
Zdroj: Journal of Medicinal Chemistry; 7/9/2020, Vol. 63 Issue 13, p7293-7325, 33p
Databáze: Supplemental Index