The effects of supplementation with L-arginine on anthropometric indices and body composition in overweight or obese subjects: A systematic review and meta-analysis.

Autor: Zeinali Khosroshahi, Mohammad, Asbaghi, Omid, Moradi, Sajjad, Rezaei kelishadi, Mahnaz, Kaviani, Mojtaba, Mardani, Mahnaz, Jalili, Cyrus
Zdroj: Journal of Functional Foods; Aug2020, Vol. 71, pN.PAG-N.PAG, 1p
Abstrakt: • L-arginine supplementation reduces BMI. • L-arginine supplementation reduces waist circumference. • L-arginine supplementation reduces fat mass. • L-arginine supplementation increases fat free mass. • L-arginine supplementation has no effect on body weight. Animal studies have shown that L-Arginine can affect anthropometric and body composition indices favorably, while results of human studies are contradictory. This is a meta -analysis of human studies in which L-arginine was provided as a dietary supplement to test its effects on anthropometric indices. We searched the Cochrane library, PubMed, Embase and Scopus databases to identify studies in which L-arginine was provided to humans in randomized clinical trials. Of 4784 publications, 12 trials were included for the meta -analysis. Pooled effect sizes indicated that L-arginine significantly reduced body mass index (BMI), waist circumference (WC), and fat mass (FM), and also increased fat-free mass (FFM) compared to the placebo group. However, the effects of L-arginine on body weight (BW) was not significant. Subgroup analysis could not identify factors significantly influencing BW. We found a beneficial effect of L-arginine supplementation on anthropometric indices in overweight and obese subjects. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index